Overview
Breast cancer is the most common cancer in Japanese women and high-quality real-world data is crucial for understanding comparative effectiveness, unmet needs, and safety; however, many existing sources often lack clinical detail. This study investigates patient profiles and testing patterns in a real-world cohort of patients with breast cancer in Japan, using the Japan Flatiron Health Research Database, derived from structured and unstructured data documented in electronic health records (EHR) during routine oncology care in Japan, and curated through technology-enabled abstraction with comprehensive quality verification processes.
By analyzing data from 1,862 patients, the study provides insight into clinical profiles, biomarker testing and positivity rates in a real-world Japanese cohort. The dataset includes a high level of detail and completeness and aligns with clinical expectations in Japan.
Why this matters
This research fills critical gaps in existing breast cancer data by offering a detailed view of real-world patient characteristics and testing trends in Japan. The ability to harmonize this dataset with international counterparts from the US, UK, and Germany allows for a global perspective on breast cancer management. Such comprehensive data supports the development of personalized treatment strategies and highlights areas for improvement in clinical practice and paves the way for more effective interventions worldwide.